The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds lipoprotein lipase and beta-migrating very low density lipoprotein associated …
A Nykjaer, G Bengtsson-Olivecrona, A Lookene… - Journal of Biological …, 1993 - ASBMB
Lipoprotein lipase (LPL) causes a marked increase in the cellular binding of beta-migrating
very low density lipoprotein (beta-VLDL) to a large receptor compatible with the alpha 2-
macroglobulin receptor (alpha 2MR)/low density lipoprotein receptor-related protein
(LRP)(Beisiegel, U., Weber, W., and Bengtsson-Olivecrona, G.(1991) Proc. Natl. Acad. Sci.
USA 88, 8342-8346). Here we demonstrate that LPL binds to the alpha-chain of purified
alpha 2MR/LRP immobilized on microtiter plates. The binding, apparently to multiple sites …
very low density lipoprotein (beta-VLDL) to a large receptor compatible with the alpha 2-
macroglobulin receptor (alpha 2MR)/low density lipoprotein receptor-related protein
(LRP)(Beisiegel, U., Weber, W., and Bengtsson-Olivecrona, G.(1991) Proc. Natl. Acad. Sci.
USA 88, 8342-8346). Here we demonstrate that LPL binds to the alpha-chain of purified
alpha 2MR/LRP immobilized on microtiter plates. The binding, apparently to multiple sites …
