DENDRITIC CELLS AS REGULATORS OF IMMUNE REACTIVITY: IMPLICATIONS FOR TRANSPLANTATION1
AW Thomson, L Lu - Transplantation, 1999 - journals.lww.com
AW Thomson, L Lu
Transplantation, 1999•journals.lww.comDendritic cells are now regarded not only as the initiators but also as regulators of immune
responses. They are potentially powerful tools for the therapeutic manipulation of immune
reactivity in cancer, infectious disease, and allograft rejection. We provide a brief overview of
the properties of dendritic cells, with emphasis on recently acquired information, then focus
attention on their capacity to modulate immune reactivity, and its relevance to
transplantation.
responses. They are potentially powerful tools for the therapeutic manipulation of immune
reactivity in cancer, infectious disease, and allograft rejection. We provide a brief overview of
the properties of dendritic cells, with emphasis on recently acquired information, then focus
attention on their capacity to modulate immune reactivity, and its relevance to
transplantation.
Abstract
Dendritic cells are now regarded not only as the initiators but also as regulators of immune responses. They are potentially powerful tools for the therapeutic manipulation of immune reactivity in cancer, infectious disease, and allograft rejection. We provide a brief overview of the properties of dendritic cells, with emphasis on recently acquired information, then focus attention on their capacity to modulate immune reactivity, and its relevance to transplantation.
Lippincott Williams & Wilkins