In situ characterization of the cell-surface antigens of the mononuclear cell infiltrate and bile duct epithelium in primary biliary cirrhosis
G Colucci, F Schaffner, F Paronetto - Clinical immunology and …, 1986 - Elsevier
To analyze the tissue distribution of mononuclear cells and HLA antigens in primary biliary
cirrhosis, we studied liver biopsies of 12 patients at different stages of the disease, using the
avidin-biotin-peroxidase technique and monoclonal antibodies directed against T and B
lymphocytes, T-cell subsets, macrophages, NK/K cells, dendritic cells, and HLA class I and II
antigens. To evaluate the proportion of activated T cells we used anti-interleukin-2-receptor
antibodies and a double-staining technique for T cells and class II HLA antigens. In all …
cirrhosis, we studied liver biopsies of 12 patients at different stages of the disease, using the
avidin-biotin-peroxidase technique and monoclonal antibodies directed against T and B
lymphocytes, T-cell subsets, macrophages, NK/K cells, dendritic cells, and HLA class I and II
antigens. To evaluate the proportion of activated T cells we used anti-interleukin-2-receptor
antibodies and a double-staining technique for T cells and class II HLA antigens. In all …