[HTML][HTML] Culture conditions affect the ability of ex vivo expanded peripheral blood progenitor cells to accelerate hematopoietic recovery

RL Paquette, ST Dergham, E Karpf, HJ Wang… - Experimental …, 2002 - Elsevier
OBJECTIVE: The aim of this study was to evaluate the effect of various ex vivo expansion
conditions on the cell products and their ability to accelerate hematopoietic recovery in
patients undergoing stem cell transplantation. Patients and Methods. Unselected peripheral
blood progenitor cells (PBPCs) from 43 breast cancer patients were seeded into gas-
permeable bags containing serum-free media, granulocyte colony-stimulating factor, stem
cell factor, and pegylated megakaryocyte growth and development factor. Between 2 and …