Lipid trafficking and sorting: how cholesterol is filling gaps
D Hoekstra, SCD van IJzendoorn - Current Opinion in Cell Biology, 2000 - Elsevier
D Hoekstra, SCD van IJzendoorn
Current Opinion in Cell Biology, 2000•ElsevierRecent research has highlighted a role for cholesterol homeostasis in the regulation of
trafficking and sorting of sphingolipids. This sorting may dictate the nature of the acyl chain
species of phospholipids in the plasma membrane which, in turn, may govern the selective
partitioning of these lipids into lateral domains. Recently, several proteins have been
identified that play a role in the flow and sorting of all major lipid classes.
trafficking and sorting of sphingolipids. This sorting may dictate the nature of the acyl chain
species of phospholipids in the plasma membrane which, in turn, may govern the selective
partitioning of these lipids into lateral domains. Recently, several proteins have been
identified that play a role in the flow and sorting of all major lipid classes.
Recent research has highlighted a role for cholesterol homeostasis in the regulation of trafficking and sorting of sphingolipids. This sorting may dictate the nature of the acyl chain species of phospholipids in the plasma membrane which, in turn, may govern the selective partitioning of these lipids into lateral domains. Recently, several proteins have been identified that play a role in the flow and sorting of all major lipid classes.
Elsevier
