Influence of endurance training on the age-related decline in hepatic glyconeogenesis
DA Podolin, MJ Pagliassotti, TT Gleeson… - Mechanisms of ageing …, 1994 - Elsevier
Hepatic gluconeogenic and glyconeogenic capabilities were investigated in Fischer 344 rat
livers (ages 7, 15 and 25 months; n= 66) to determine if endurance training affected age
related decrements in these hepatic functions. Animals were trained 1 h/day, 5 days/week
for 10 weeks at treadmill speeds of 75% of age-specific maximal capacity. After training, rats
were injected (300 mg/kg) with a known gluconeogenic inhibitor, 3-mercaptopicolinic acid
(MPA). Two endurance tests were performed to help assess the contribution of …
livers (ages 7, 15 and 25 months; n= 66) to determine if endurance training affected age
related decrements in these hepatic functions. Animals were trained 1 h/day, 5 days/week
for 10 weeks at treadmill speeds of 75% of age-specific maximal capacity. After training, rats
were injected (300 mg/kg) with a known gluconeogenic inhibitor, 3-mercaptopicolinic acid
(MPA). Two endurance tests were performed to help assess the contribution of …