Neutrophil migration through preexisting holes in the basal laminae of alveolar capillaries and epithelium during streptococcal pneumonia
DC Walker, AR Behzad, F Chu - Microvascular research, 1995 - Elsevier
The purpose of this study was to determine whether or not there are preexisting holes in the
endothelial and epithelial basal laminae of alveolar walls and to determine the path taken by
neutrophils as they migrate from the capillaries to the airspace of the alveoli during
inflammation. Using transmission electron microscopy and serial thin sections of normal
rabbit and mouse lung, we have demonstrated the presence of slit-like holes in the capillary
basal laminae and round holes in the basal laminae of type 2 pneumocytes. The slits in the …
endothelial and epithelial basal laminae of alveolar walls and to determine the path taken by
neutrophils as they migrate from the capillaries to the airspace of the alveoli during
inflammation. Using transmission electron microscopy and serial thin sections of normal
rabbit and mouse lung, we have demonstrated the presence of slit-like holes in the capillary
basal laminae and round holes in the basal laminae of type 2 pneumocytes. The slits in the …
