Lung cancer screening with helical computed tomography in older adult smokers: a decision and cost-effectiveness analysis

PJ Mahadevia, LA Fleisher, KD Frick, J Eng… - Jama, 2003 - jamanetwork.com
Context Encouraged by direct-to-consumer marketing, smokers and their physicians are
contemplating lung cancer screening with a promising but unproven imaging procedure,
helical computed tomography (CT). Objective To estimate the potential benefits, harms, and
cost-effectiveness of lung cancer screening with helical CT in various efficacy scenarios.
Design, Setting, and Population Using a computer-simulated model, we compared annual
helical CT screening to no screening for hypothetical cohorts of 100 000 current, quitting …