[HTML][HTML] Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK) 293 cells: evidence for a non-capacitative Ca2+ entry
Ca 2+ release from its internal stores as a result of activation of phospholipase C is
accompanied by Ca 2+ influx from the extracellular space. Ca 2+ influx channels may be
formed of proteins homologous toDrosophila Trp. At least six non-allelic Trpgenes are
present in the mouse genome. Full-length human, bovine, mouse, and rat cDNAs for Trp1, 3,
4, 6 have been cloned. Expression of these genes in various mammalian cells has provided
evidence that Trp proteins form plasma membrane Ca 2+-permeant channels that can be …
accompanied by Ca 2+ influx from the extracellular space. Ca 2+ influx channels may be
formed of proteins homologous toDrosophila Trp. At least six non-allelic Trpgenes are
present in the mouse genome. Full-length human, bovine, mouse, and rat cDNAs for Trp1, 3,
4, 6 have been cloned. Expression of these genes in various mammalian cells has provided
evidence that Trp proteins form plasma membrane Ca 2+-permeant channels that can be …