The Epidemiology of Chlamydia trachomatis within a Sexually Transmitted Diseases Core Group
Journal of Infectious Diseases, 1996•academic.oup.com
Female sex workers in Nairobi were prospectively evaluated for risk factors of incident
Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P=. 007),
gonococcal infection (P=. 002), human immunodeficiency virus (HIV) seropositivity (P=.
003), HIV seroconversion (P=. 001), and duration of prostitution (P=. 002). Eighteen different
C. trachomatis outer membrane protein (omp1) genotypes were identified, with the allelic
composition of the C. trachomatis population changing significantly over time (P=. 005) …
Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P=. 007),
gonococcal infection (P=. 002), human immunodeficiency virus (HIV) seropositivity (P=.
003), HIV seroconversion (P=. 001), and duration of prostitution (P=. 002). Eighteen different
C. trachomatis outer membrane protein (omp1) genotypes were identified, with the allelic
composition of the C. trachomatis population changing significantly over time (P=. 005) …
Abstract
Female sex workers in Nairobi were prospectively evaluated for risk factors of incident Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P = .007), gonococcal infection (P = .002), human immunodeficiency virus (HIV) seropositivity (P = .003), HIV seroconversion (P = .001), and duration of prostitution (P = .002). Eighteen different C. trachomatis outer membrane protein (omp1) genotypes were identified, with the allelic composition of the C. trachomatis population changing significantly over time (P = .005). Seventeen of 19 reinfections ⩾6 months apart were with different C. trachomatis ompi genotypes. Women with HIV infection had an increased proportion of visits with C. trachomatis infection (P = .001) and an increased risk of reinfection (P = .008). Overall, the data demonstrate significant fluctuations in the genotype composition of the C. trachomatis population and a reduced rate of same-genotype reinfection consistent with the occurrence of strain-specific immunity.
Oxford University Press