Receptor-mediated uptake of lipoprotein-cholesterol and its utilization for steroid synthesis in the adrenal cortex
MS BROWN, PT KOVANEN, JL GOLDSTEIN - Proceedings of the 1978 …, 1979 - Elsevier
Publisher Summary This chapter discusses the receptor-mediated uptake of lipoprotein
cholesterol and its utilization for steroid synthesis in the adrenal cortex. It discusses the four
model system (1) mouse adrenal tumor cells in culture (Y-1 clone),(2) rats treated in vivo
with 4-aminopyrazolopyrimidine (4-APP),(3) bovine adrenal cortex, and (4) Human fetal
adrenal membranes to demonstrate the presence and physiological significance of low-
density lipoprotein. The studies in the four model systems allow the formulation of a …
cholesterol and its utilization for steroid synthesis in the adrenal cortex. It discusses the four
model system (1) mouse adrenal tumor cells in culture (Y-1 clone),(2) rats treated in vivo
with 4-aminopyrazolopyrimidine (4-APP),(3) bovine adrenal cortex, and (4) Human fetal
adrenal membranes to demonstrate the presence and physiological significance of low-
density lipoprotein. The studies in the four model systems allow the formulation of a …