[HTML][HTML] Hypothalamic responses to long-chain fatty acids are nutritionally regulated
K Morgan, S Obici, L Rossetti - Journal of Biological Chemistry, 2004 - ASBMB
Central administration of the long-chain fatty acid oleic acid inhibits food intake and glucose
production in rats. Here we examined whether short term changes in nutrient availability can
modulate these metabolic and behavioral effects of oleic acid. Rats were divided in three
groups receiving a highly palatable energy-dense diet at increasing daily caloric levels
(below, similar, or above the average of rats fed standard chow). Following 3 days on the
assigned diet regimen, rats were tested for acute biological responses to the infusion of oleic …
production in rats. Here we examined whether short term changes in nutrient availability can
modulate these metabolic and behavioral effects of oleic acid. Rats were divided in three
groups receiving a highly palatable energy-dense diet at increasing daily caloric levels
(below, similar, or above the average of rats fed standard chow). Following 3 days on the
assigned diet regimen, rats were tested for acute biological responses to the infusion of oleic …