Iron is essential for both host and pathogen, and complex systems of acquisition and
utilization have evolved in competition. Our increasing knowledge of the basic mechanisms
of homeostasis and their adaptation during deficiency, overload, and infection indicate that
iron is a key regulator of host pathogen interactions. This review concentrated on the clinical
and public health aspects of the interaction between the iron acquisition mechanisms of
select pathogens of public health importance with host iron homeostasis. Knowledge of …