[HTML][HTML] Human CCAAT/enhancer-binding protein β gene expression is activated by endoplasmic reticulum stress through an unfolded protein response element …

C Chen, EE Dudenhausen, YX Pan, C Zhong… - Journal of Biological …, 2004 - ASBMB
CCAAT/enhancer-binding protein β (C/EBPβ) is a member of the bZIP family of transcription
factors that contribute to the regulation of a wide range of important cellular processes. The
data in the present study document that transcription from the human C/EBPβ gene is
induced in response to endoplasmic reticulum stress, such as glucose deprivation, or
treatment of cells with tunicamycin or thapsigargin. Transient transfection of C/EBPβ
genomic fragments linked to a luciferase reporter gene demonstrated that the C/EBPβ …