[HTML][HTML] Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment
Background: Body mass index (BMI) has been shown to be highly heritable, but most
studies were carried out in cohorts born before the onset of the “obesity epidemic.”
Objective: We aimed to quantify genetic and environmental influences on BMI and central
adiposity in children growing up during a time of dramatic rises in pediatric obesity. Design:
We carried out twin analyses of BMI and waist circumference (WC) in a UK sample of 5092
twin pairs aged 8–11 y. Quantitative genetic model-fitting was used for the univariate …
studies were carried out in cohorts born before the onset of the “obesity epidemic.”
Objective: We aimed to quantify genetic and environmental influences on BMI and central
adiposity in children growing up during a time of dramatic rises in pediatric obesity. Design:
We carried out twin analyses of BMI and waist circumference (WC) in a UK sample of 5092
twin pairs aged 8–11 y. Quantitative genetic model-fitting was used for the univariate …