Tissue-specific distribution and developmental regulation of M and B creatine kinase mRNAs
RV Trask, JJ Billadello - Biochimica et Biophysica Acta (BBA)-Gene …, 1990 - Elsevier
To characterize the tissue-specific distribution and developmentally regulated expression of
M and B creatine kinase mRNA in rats, total cellular RNA was isolated from adult rat tissues
and from skeletal muscle, heart, brain and intestine at selected stages of development.
Northern blots were prepared and hybridized with M and B subunit-specific probes derived
from the 3′-untranslated region. M creatine kinase mRNA was expressed abundantly in
heart and skeletal muscle, and less abundantly in lung. B creatine kinase mRNA was found …
M and B creatine kinase mRNA in rats, total cellular RNA was isolated from adult rat tissues
and from skeletal muscle, heart, brain and intestine at selected stages of development.
Northern blots were prepared and hybridized with M and B subunit-specific probes derived
from the 3′-untranslated region. M creatine kinase mRNA was expressed abundantly in
heart and skeletal muscle, and less abundantly in lung. B creatine kinase mRNA was found …
