Role of the autonomic nervous system in the mediation of LHA electrical stimulation-induced effects on insulinemia and glycemia

HR Berthoud, DA Bereiter, B Jeanrenaud - Journal of the Autonomic …, 1980 - Elsevier
The short-term effects of bilateral electrical stimulation of the lateral component of the lateral
hypothalamic/medial forebrain bundle area (LHA) on peripheral plasma levels of glucose
(G), immunoreactive insulin (IRI) and glucagon (IRG) were measured in food-deprived,
anesthetized rats in the presence of continous low iv glucose infusion. In normal rats LHA
stimulation induced a rapid but moderate rise in IRI in the presence of a simultaneous rapid
rise in G. At the end of the 5 min stimulation period the glucose-induced IRI response was …