Structure, mapping, and expression of human SOX18.
DJ Pennisi, KM James, B Hosking… - Mammalian …, 2000 - search.ebscohost.com
DJ Pennisi, KM James, B Hosking, GEO Muscat, P Koopman
Mammalian Genome, 2000•search.ebscohost.comThe article informs about structure, mapping, and expression of human SOX18 genes. SOX
genes are found throughout the animal kingdom and encode a highly conserved family of
transcription factors involved in a wide range of developmental processes. Several SOX
genes have been implicated in inherited human disorders: SRY in male-to-female sex
reversal and gonadal dysgenesis; SOX9 in the skeletal dysmorphogenesis syndrome
campomelic dysplasia. Furthermore, targeted disruption in mice has demonstrated vital roles …
genes are found throughout the animal kingdom and encode a highly conserved family of
transcription factors involved in a wide range of developmental processes. Several SOX
genes have been implicated in inherited human disorders: SRY in male-to-female sex
reversal and gonadal dysgenesis; SOX9 in the skeletal dysmorphogenesis syndrome
campomelic dysplasia. Furthermore, targeted disruption in mice has demonstrated vital roles …
Abstract
The article informs about structure, mapping, and expression of human SOX18 genes. SOX genes are found throughout the animal kingdom and encode a highly conserved family of transcription factors involved in a wide range of developmental processes. Several SOX genes have been implicated in inherited human disorders: SRY in male-to-female sex reversal and gonadal dysgenesis; SOX9 in the skeletal dysmorphogenesis syndrome campomelic dysplasia. Furthermore, targeted disruption in mice has demonstrated vital roles for Sox4 in cardiac development, Sox9 in chondrogenesis and Sox1 in lens development.
search.ebscohost.com