[HTML][HTML] Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to …
M Nagira, T Imai, K Hieshima, J Kusuda… - Journal of Biological …, 1997 - ASBMB
By searching the Expressed Sequence Tag (EST) data base, we identified partial cDNA
sequences potentially encoding a novel human CC chemokine. We determined the entire
cDNA sequence which encodes a highly basic polypeptide of 134 amino acids total with a
putative signal peptide of 23 amino acids. The predicted mature protein of 111 amino acids
has the four canonical cysteine residues and shows 21–33% identity to other human CC
chemokines, but has a unique carboxyl-terminal extension of about 30 amino acids which …
sequences potentially encoding a novel human CC chemokine. We determined the entire
cDNA sequence which encodes a highly basic polypeptide of 134 amino acids total with a
putative signal peptide of 23 amino acids. The predicted mature protein of 111 amino acids
has the four canonical cysteine residues and shows 21–33% identity to other human CC
chemokines, but has a unique carboxyl-terminal extension of about 30 amino acids which …