The role of neurotensin in central nervous system pathophysiology: what is the evidence?
F St-Gelais, C Jomphe, LÉ Trudeau - Journal of Psychiatry and …, 2006 - jpn.ca
The peptide neurotensin has been studied for more than 30 years. Although it is widely
distributed in the central and peripheral nervous systems, neurotensin has been more
intensely studied with regard to its interactions with the central dopamine system. A number
of claims have been made regarding its possible implication in many diseases of the central
nervous system, including schizophrenia. In this review, we describe briefly the basic
biology of this neuropeptide, and then we consider the strengths and the weaknesses of the …
distributed in the central and peripheral nervous systems, neurotensin has been more
intensely studied with regard to its interactions with the central dopamine system. A number
of claims have been made regarding its possible implication in many diseases of the central
nervous system, including schizophrenia. In this review, we describe briefly the basic
biology of this neuropeptide, and then we consider the strengths and the weaknesses of the …
