Importance New data and antiretroviral regimens expand treatment choices in resource-rich
settings and warrant an update of recommendations to treat adults infected with human
immunodeficiency virus (HIV). Objective To provide updated treatment recommendations for
adults with HIV, emphasizing when to start treatment; what treatment to start; the use of
laboratory monitoring tools; and managing treatment failure, switches, and simplification.
Data Sources, Study Selection, and Data Synthesis An International Antiviral Society–USA …