Parental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspring
DM Lloyd-Jones, BH Nam, RB D'Agostino Sr, D Levy… - Jama, 2004 - jamanetwork.com
ContextWhether parental cardiovascular disease confers increased risk independent of
other risk factors remains controversial. Prior studies relied on offspring report, without
complete validation of parental events. ObjectiveTo determine whether parental
cardiovascular disease predicts offspring events independent of traditional risk factors, using
a prospective design for both parents and offspring, and uniform criteria to validate events.
DesignInception cohort study. SettingFramingham Heart Study, a US population-based …
other risk factors remains controversial. Prior studies relied on offspring report, without
complete validation of parental events. ObjectiveTo determine whether parental
cardiovascular disease predicts offspring events independent of traditional risk factors, using
a prospective design for both parents and offspring, and uniform criteria to validate events.
DesignInception cohort study. SettingFramingham Heart Study, a US population-based …
