Macrophage activation markers predict mortality in patients with liver cirrhosis without or with acute-on-chronic liver failure (ACLF)
H Grønbæk, S Rødgaard-Hansen, NK Aagaard… - Journal of …, 2016 - Elsevier
Background & Aims Activation of liver macrophages plays a key role in liver and systemic
inflammation and may be involved in development and prognosis of acute-on-chronic liver
failure (ACLF). We therefore measured the circulating macrophage activation markers
soluble sCD163 and mannose receptor (sMR) and related them to the short-(1–3 months)
and long-term (6 months) mortality in the cirrhosis patients of the CANONIC study. Methods
Eighty-six cirrhosis patients had no ascites and no ACLF, 580 had ascites but no ACLF; 100 …
inflammation and may be involved in development and prognosis of acute-on-chronic liver
failure (ACLF). We therefore measured the circulating macrophage activation markers
soluble sCD163 and mannose receptor (sMR) and related them to the short-(1–3 months)
and long-term (6 months) mortality in the cirrhosis patients of the CANONIC study. Methods
Eighty-six cirrhosis patients had no ascites and no ACLF, 580 had ascites but no ACLF; 100 …
