Renal L-type fatty acid–binding protein in acute ischemic injury
Fatty acid–binding proteins (FABPs) bind unsaturated fatty acids and lipid peroxidation
products during tissue injury from hypoxia. We evaluated the potential role of L-type FABP (L-
FABP) as a biomarker of renal ischemia in both human kidney transplant patients and
animal models. Urinary L-FABP levels were measured in the first urine produced from 12
living-related kidney transplant patients immediately after reperfusion of their transplanted
organs, and intravital video analysis of peritubular capillary blood flow was performed …
products during tissue injury from hypoxia. We evaluated the potential role of L-type FABP (L-
FABP) as a biomarker of renal ischemia in both human kidney transplant patients and
animal models. Urinary L-FABP levels were measured in the first urine produced from 12
living-related kidney transplant patients immediately after reperfusion of their transplanted
organs, and intravital video analysis of peritubular capillary blood flow was performed …