Obesity, intrapancreatic fatty infiltration, and pancreatic cancer
Obesity and intrapancreatic fatty infiltration are associated with increased risk of pancreatic
cancer and its precursor lesions. The interplay among obesity, inflammation, and oncogenic
Kras signaling promotes pancreatic tumorigenesis. Targeting the interaction between
obesity-associated inflammation and Kras signaling may provide new strategies for
prevention and therapy of pancreatic cancer. Clin Cancer Res; 21 (15); 3369–71.© 2015
AACR. See related article by Rebours et al., p. 3522
cancer and its precursor lesions. The interplay among obesity, inflammation, and oncogenic
Kras signaling promotes pancreatic tumorigenesis. Targeting the interaction between
obesity-associated inflammation and Kras signaling may provide new strategies for
prevention and therapy of pancreatic cancer. Clin Cancer Res; 21 (15); 3369–71.© 2015
AACR. See related article by Rebours et al., p. 3522
Abstract
Obesity and intrapancreatic fatty infiltration are associated with increased risk of pancreatic cancer and its precursor lesions. The interplay among obesity, inflammation, and oncogenic Kras signaling promotes pancreatic tumorigenesis. Targeting the interaction between obesity-associated inflammation and Kras signaling may provide new strategies for prevention and therapy of pancreatic cancer. Clin Cancer Res; 21(15); 3369–71. ©2015 AACR.
See related article by Rebours et al., p. 3522
AACR