[HTML][HTML] Early reduction of regulatory T cells is associated with acute rejection in liver transplantation under tacrolimus-based immunosuppression with basiliximab …
Regulatory T (Treg) cells are important in preventing acute rejection (AR) in solid organ
transplantation, but the clinical relevance of the different kinetics early after liver
transplantation (LT) in acute rejectors and non-rejectors is unclear. We analyzed peripheral
blood samples of 128 LT recipients receiving basiliximab induction plus tacrolimus
immunosuppression. Samples were obtained at pretransplant, D7, and D30 after LT.
Frequency and phenotype of Tregs were analyzed by flow cytometry. The predictive value of …
transplantation, but the clinical relevance of the different kinetics early after liver
transplantation (LT) in acute rejectors and non-rejectors is unclear. We analyzed peripheral
blood samples of 128 LT recipients receiving basiliximab induction plus tacrolimus
immunosuppression. Samples were obtained at pretransplant, D7, and D30 after LT.
Frequency and phenotype of Tregs were analyzed by flow cytometry. The predictive value of …