Topical rapamycin combined with pulsed dye laser in the treatment of capillary vascular malformations in Sturge-Weber syndrome: phase II, randomized, double-blind …
L Marqués, JM Núñez-Córdoba, L Aguado… - Journal of the American …, 2015 - Elsevier
Background Sturge-Weber syndrome (SWS) is characterized by port-wine stains (PWS)
affecting the face, eyes, and central nervous system. Pulsed dye laser (PDL) is the standard
treatment for PWS. Unfortunately, recurrence is frequent because of reformation and
reperfusion of blood vessels. Objective We sought to assess the clinical efficacy of topical
rapamycin combined with PDL in PWS of patients with SWS. Methods We conducted a
phase II, randomized, double-blind, intraindividual placebo-controlled, clinical trial. We …
affecting the face, eyes, and central nervous system. Pulsed dye laser (PDL) is the standard
treatment for PWS. Unfortunately, recurrence is frequent because of reformation and
reperfusion of blood vessels. Objective We sought to assess the clinical efficacy of topical
rapamycin combined with PDL in PWS of patients with SWS. Methods We conducted a
phase II, randomized, double-blind, intraindividual placebo-controlled, clinical trial. We …
