[HTML][HTML] Observations on enhanced port wine stain blanching induced by combined pulsed dye laser and rapamycin administration
JS Nelson, W Jia, TL Phung… - Lasers in surgery and …, 2011 - ncbi.nlm.nih.gov
JS Nelson, W Jia, TL Phung, MC Mihm Jr
Lasers in surgery and medicine, 2011•ncbi.nlm.nih.govPort wine stain (PWS) is a congenital, progressive vascular malformation of skin involving
post-capillary venules that occurs in an estimated 3–4 children per 1,000 live births (1–3).
Since most malformations occur on the face and neck, PWS is a clinically significant problem
in the majority of patients. PWS are initially flat red macules that can be localized or
segmental, but lesions tend to darken progressively, and by middle age, often transform into
dark-red or purple plaques with nodularity (4, 5). The pulsed dye laser (PDL) is the current …
post-capillary venules that occurs in an estimated 3–4 children per 1,000 live births (1–3).
Since most malformations occur on the face and neck, PWS is a clinically significant problem
in the majority of patients. PWS are initially flat red macules that can be localized or
segmental, but lesions tend to darken progressively, and by middle age, often transform into
dark-red or purple plaques with nodularity (4, 5). The pulsed dye laser (PDL) is the current …
Port wine stain (PWS) is a congenital, progressive vascular malformation of skin involving post-capillary venules that occurs in an estimated 3–4 children per 1,000 live births (1–3). Since most malformations occur on the face and neck, PWS is a clinically significant problem in the majority of patients. PWS are initially flat red macules that can be localized or segmental, but lesions tend to darken progressively, and by middle age, often transform into dark-red or purple plaques with nodularity (4, 5).
The pulsed dye laser (PDL) is the current treatment of choice for PWS. Yellow light is preferentially absorbed by hemoglobin in PWS blood vessels where, after being converted to heat, causes thermal damage and thrombosis. Treatment is often followed by temporary purpura, which resolves in 7–14 days.
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